Polymeric nanoparticles are nanoscale particles made from natural or synthetic polymers, typically ranging from 10-1000 nm in size. These biodegradable or biocompatible materials are particularly valuable in pharmaceutical and biomedical applications due to their ability to encapsulate drugs and release them in controlled manners.
Types of Polymeric Nanoparticles:
Nanospheres: Solid polymer matrix where drugs are dissolved or dispersed throughout the structure
Nanocapsules: Hollow core surrounded by a polymer shell, with drugs contained in the liquid core
Common Polymer Materials:
Key Advantages:
Applications:
Manufacturing Considerations: Polymeric nanoparticles are typically produced through emulsification, nanoprecipitation, or ionic gelation methods. Control over particle size, drug loading efficiency, and release kinetics is critical for pharmaceutical applications. Continuous flow systems enable precise control over these parameters, producing consistent polymeric nanoparticles suitable for clinical use.